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Constitutive activation of integrin αvβthree influences SERT perform inside the Grownup animal, effects that could be recapitulated, or reversed, by pharmacologically focusing on tyrosine kinases within an ex vivo
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= 5 for each genotype). These results suggest which the modifications in SERT operate in KI mice have been probable a results of lessened catalytic activity, exactly where the transport of each 5-HT molecule (
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